Srila Narottama dasa Thakura says, samsara-visanale, divanisi hiya jvale, judaite na kainu upaya: “We are always suffering from material pangs, and our hearts are burning, but we cannot find any way out of it.” The materialistic person can also be called a tapasvi, which means someone who is always suffering from material pains. One can get rid of all these material pains only when he takes shelter of the chanting of the Hare Krsna mantra. This is also explained by Narottama dasa Thakura: golokera prema-dhana, hari-nama-sankirtana, rati na janmila kene taya. Narottama dasa Thakura regretted that he did not pursue his attraction for the transcendental vibration of the Hare Krsna mantra. The conclusion is that all persons in this material world are suffering from material pains, and if one wants to get rid of them, he must associate with saintly persons, pure devotees of the Lord, and chant the maha-mantra, Hare Krsna, Hare Krsna, Krsna Krsna, Hare Hare / Hare Rama, Hare Rama, Rama Rama, Hare Hare. That is the only auspicious way for materialistic persons.
—Srila Prabhupada, Srimad-Bhagavatam 4.22.15 purport